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FAM3A mediates PPARγ's protection in liver ischemia-reperfusion injury by activating Akt survival pathway and repressing inflammation and oxidative stress

FAM3A is a novel mitochondrial protein, and its biological function remains largely unknown. This study determined the role and mechanism of FAM3A in liver ischemia-reperfusion injury (IRI). In mouse liver after IRI, FAM3A expression was increased. FAM3A-deficient mice exhibited exaggerated liver da...

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Detalles Bibliográficos
Autores principales:	Chen, Zhenzhen, Wang, Junpei, Yang, Weili, Chen, Ji, Meng, Yuhong, Geng, Bin, Cui, Qinghua, Yang, Jichun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564815/ https://www.ncbi.nlm.nih.gov/pubmed/28562339 http://dx.doi.org/10.18632/oncotarget.17805

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