Cargando…

Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF-β1-SMAD3-ID1 signaling pathway

Human gallbladder cancer (GBC) is a lethal aggressive malignant neoplasm. Identification of potential molecular biomarkers and development of targeted therapeutics for GBC patients is very necessary. In this study, we firstly investigated the correlation between ring finger protein 125 (RNF125) expr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Zhong-Yan, Cao, Jin, Zhang, Jing-Tao, Xu, Guo-Li, Li, Xin-Ping, Wang, Fang-Tao, Ansari, Kamar Hasan, Mohamed, Hassan, Fan, Yue-Zu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564816/ https://www.ncbi.nlm.nih.gov/pubmed/28611292 http://dx.doi.org/10.18632/oncotarget.18180

Ejemplares similares

High Expression of RING Finger Protein 126 Predicts Unfavorable Prognosis of Epithelial Ovarian Cancer
por: Wang, Chuanjiang, et al.
Publicado: (2020)

Ring Finger Protein 125 Is an Anti-Proliferative Tumor Suppressor in Hepatocellular Carcinoma
por: Kodama, Takahiro, et al.
Publicado: (2022)

ID1 and ID4 Are Biomarkers of Tumor Aggressiveness and Poor Outcome in Immunophenotypes of Breast Cancer
por: Garcia-Escolano, Marta, et al.
Publicado: (2021)

Oncogenic Herpesvirus KSHV Hijacks BMP-Smad1-Id Signaling to Promote Tumorigenesis
por: Liang, Deguang, et al.
Publicado: (2014)

Establishment and characterization of a novel highly aggressive gallbladder cancer cell line, TJ-GBC2
por: Liu, Zhong-Yan, et al.
Publicado: (2017)

Correction: Oncogenic Herpesvirus KSHV Hijacks BMP-Smad1-Id Signaling to Promote Tumorigenesis
por: Liang, Deguang, et al.
Publicado: (2022)

Gallbladder cancer-associated fibroblasts promote vasculogenic mimicry formation and tumor growth in gallbladder cancer via upregulating the expression of NOX4, a poor prognosis factor, through IL-6-JAK-STAT3 signal pathway
por: Pan, Mu-Su, et al.
Publicado: (2020)

Smad7-overexpressing rat BMSCs inhibit the fibrosis of hepatic stellate cells by regulating the TGF-β1/Smad signaling pathway
por: Wu, Shi-Pin, et al.
Publicado: (2017)

LASP1-S100A11 axis promotes colorectal cancer aggressiveness by modulating TGFβ/Smad signaling
por: Niu, Ya, et al.
Publicado: (2016)

Correction to: Gallbladder cancer-associated fibroblasts promote vasculogenic mimicry formation and tumor growth in gallbladder cancer via upregulating the expression of NOX4, a poor prognosis factor, through IL-6-JAK-STAT3 signal pathway
por: Pan, Mu-Su, et al.
Publicado: (2021)

Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cells
por: Jiang, L, et al.
Publicado: (2017)

circMTO1 sponges microRNA-219a-5p to enhance gallbladder cancer progression via the TGF-β/Smad and EGFR pathways
por: Wang, Pingfan, et al.
Publicado: (2021)

Iodine-125 Seeds Inhibit Carcinogenesis of Hepatocellular Carcinoma Cells by Suppressing Epithelial-Mesenchymal Transition via TGF-β1/Smad Signaling
por: Yang, Chongshuang, et al.
Publicado: (2022)

IL-1β Promotes Stemness of Tumor Cells by Activating Smad/ID1 Signaling Pathway
por: Lu, Lin, et al.
Publicado: (2020)

The expression of TGF-β1, Smad3, phospho-Smad3 and Smad7 is correlated with the development and invasion of nonfunctioning pituitary adenomas
por: Zhenye, Li, et al.
Publicado: (2014)

DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling
por: Chan, D W, et al.
Publicado: (2017)

RING finger 138 deregulation distorts NF-кB signaling and facilities colitis switch to aggressive malignancy
por: Lu, Yalan, et al.
Publicado: (2022)

Baicalin and puerarin reverse epithelial-mesenchymal transition via the TGF-β1/Smad3 pathway in vitro
por: Wu, Tao, et al.
Publicado: (2018)

The ALK1-Smad1/5-ID1 pathway participates in tumour angiogenesis induced by low-dose photodynamic therapy
por: Guo, Xiya, et al.
Publicado: (2023)

G3BP1 activates the TGF-β/Smad signaling pathway to promote gastric cancer
por: Xiong, Rui, et al.
Publicado: (2019)

Correction: Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cells
por: Jiang, L., et al.
Publicado: (2022)

TGF‐β1 promotes gap junctions formation in chondrocytes via Smad3/Smad4 signalling
por: Wang, Qingxuan, et al.
Publicado: (2018)

The effect of TGF-β1 and Smad7 gene transfer on the phenotypic changes of rat alveolar epithelial cells
por: Xu, Guo-Ping, et al.
Publicado: (2007)

Rejuvenation by inhibiting TGF-β1/pSmad signaling
por: Corder, Elizabeth H., et al.
Publicado: (2015)

Decreased zinc-fingers and homeoboxes family expression was associated with unfavorable outcomes and immune infiltration in lung adenocarcinoma
por: Tao, Dan, et al.
Publicado: (2023)

Syndecan-1 Amplifies Ovalbumin-Induced Airway Remodeling by Strengthening TGFβ1/Smad3 Action
por: Zhang, Dong, et al.
Publicado: (2021)

TGF-β1-Smad signaling pathways are not required for epidermal LC homeostasis
por: Li, Guihua, et al.
Publicado: (2016)

Aspirin inhibits endometrial fibrosis by suppressing the TGF-β1-Smad2/Smad3 pathway in intrauterine adhesions
por: Zhang, Zihui, et al.
Publicado: (2020)

Inhibition of Wilms' Tumor Proliferation and Invasion by Blocking TGF-β Receptor I in the TGF-β/Smad Signaling Pathway
por: Shi, Qinlin, et al.
Publicado: (2020)

NANOG regulates the proliferation of PCSCs via the TGF-β1/SMAD pathway
por: Liu, Changming, et al.
Publicado: (2020)

Atorvastatin attenuates TGF-β1-induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts
por: Du, Yanfei, et al.
Publicado: (2020)

Sarcomatoid carcinoma of the gallbladder: A rare and aggressive form of gallbladder cancer
por: Limaiem, Faten, et al.
Publicado: (2023)

Preliminary ID designs for the LSB storage ring
por: Queralt, X
Publicado: (1996)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

High-dose TGF-β1 degrades human nucleus pulposus cells via ALK1-Smad1/5/8 activation
por: Qu, Zhiqiang, et al.
Publicado: (2020)

A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125
por: Bijlmakers, Marie-José, et al.
Publicado: (2016)

BRCA1 Interacts with Smad3 and Regulates Smad3-Mediated TGF-β Signaling during Oxidative Stress Responses
por: Li, Huchun, et al.
Publicado: (2009)

ID1 and ID3 are Negative Regulators of TGFβ2-Induced Ocular Hypertension and Compromised Aqueous Humor Outflow Facility in Mice
por: Mody, Avani A., et al.
Publicado: (2021)

Serum CXCL13 Level is Associated with Tumor Progression and Unfavorable Prognosis in Penile Cancer
por: Mo, Miao, et al.
Publicado: (2020)

EZH2 is involved in psoriasis progression by impairing miR-125a-5p inhibition of SFMBT1 and leading to inhibition of the TGFβ/SMAD pathway
por: Qu, Shengming, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a1g0vs1dlrig5nngqgk6jit171