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Increased serum resistin level is associated with coronary heart disease
To explore the relationship between the serum resistin level and different types of coronary heart diseases (CHD). Literature was retrieved by formal searching of PubMed, Web of Science, Google Scholar, the Cochrane Library, Wanfang Data, China Biological Medicine Database (SinoMed) and China Nation...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564838/ https://www.ncbi.nlm.nih.gov/pubmed/28404934 http://dx.doi.org/10.18632/oncotarget.15707 |
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author | Zhang, Jing-Zhan Gao, Ying Zheng, Ying-Ying Liu, Fen Yang, Yi-Ning Li, Xiao-Mei Ma, Xiang Ma, Yi-Tong Xie, Xiang |
author_facet | Zhang, Jing-Zhan Gao, Ying Zheng, Ying-Ying Liu, Fen Yang, Yi-Ning Li, Xiao-Mei Ma, Xiang Ma, Yi-Tong Xie, Xiang |
author_sort | Zhang, Jing-Zhan |
collection | PubMed |
description | To explore the relationship between the serum resistin level and different types of coronary heart diseases (CHD). Literature was retrieved by formal searching of PubMed, Web of Science, Google Scholar, the Cochrane Library, Wanfang Data, China Biological Medicine Database (SinoMed) and China National Knowledge Infrastructure (CNKI) and by hand searching of reference lists of related articles. RevMan5.3 statistical software was utilized for processing and analysis. A total of 22 literatures involving 2070 subjects were included. Meta-analysis showed that the level of serum resistin in the patients with stable angina (SA), unstable angina(UA) or acute myocardial infarction (AMI) were significantly higher than those of normal controls, respectively [SMD(95% CI) were 1.97(1.15, 2.79), 2.54(1.76, 3.31), and 3.62(2.62, 4.62), all P<0.00001]. Serum resistin level in patients with UA or AMI was higher than those in patients with SA, respectively [SMD=0.90, 95CI(0.28,1.52), P=0.005], [SMD=2.28, 95%CI(0.74, 3.82), P=0.004]. The level of serum resistin in patients with AMI was also higher than those in patients with UA [SMD=1.22, 95%CI(0.58, 1.85), P=0.0002]. The study demonstrated that increased serum resistin level is significantly associated with the severity of CHD. |
format | Online Article Text |
id | pubmed-5564838 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Impact Journals LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-55648382017-08-23 Increased serum resistin level is associated with coronary heart disease Zhang, Jing-Zhan Gao, Ying Zheng, Ying-Ying Liu, Fen Yang, Yi-Ning Li, Xiao-Mei Ma, Xiang Ma, Yi-Tong Xie, Xiang Oncotarget Clinical Research Paper To explore the relationship between the serum resistin level and different types of coronary heart diseases (CHD). Literature was retrieved by formal searching of PubMed, Web of Science, Google Scholar, the Cochrane Library, Wanfang Data, China Biological Medicine Database (SinoMed) and China National Knowledge Infrastructure (CNKI) and by hand searching of reference lists of related articles. RevMan5.3 statistical software was utilized for processing and analysis. A total of 22 literatures involving 2070 subjects were included. Meta-analysis showed that the level of serum resistin in the patients with stable angina (SA), unstable angina(UA) or acute myocardial infarction (AMI) were significantly higher than those of normal controls, respectively [SMD(95% CI) were 1.97(1.15, 2.79), 2.54(1.76, 3.31), and 3.62(2.62, 4.62), all P<0.00001]. Serum resistin level in patients with UA or AMI was higher than those in patients with SA, respectively [SMD=0.90, 95CI(0.28,1.52), P=0.005], [SMD=2.28, 95%CI(0.74, 3.82), P=0.004]. The level of serum resistin in patients with AMI was also higher than those in patients with UA [SMD=1.22, 95%CI(0.58, 1.85), P=0.0002]. The study demonstrated that increased serum resistin level is significantly associated with the severity of CHD. Impact Journals LLC 2017-02-25 /pmc/articles/PMC5564838/ /pubmed/28404934 http://dx.doi.org/10.18632/oncotarget.15707 Text en Copyright: © 2017 Zhang et al. http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Clinical Research Paper Zhang, Jing-Zhan Gao, Ying Zheng, Ying-Ying Liu, Fen Yang, Yi-Ning Li, Xiao-Mei Ma, Xiang Ma, Yi-Tong Xie, Xiang Increased serum resistin level is associated with coronary heart disease |
title | Increased serum resistin level is associated with coronary heart disease |
title_full | Increased serum resistin level is associated with coronary heart disease |
title_fullStr | Increased serum resistin level is associated with coronary heart disease |
title_full_unstemmed | Increased serum resistin level is associated with coronary heart disease |
title_short | Increased serum resistin level is associated with coronary heart disease |
title_sort | increased serum resistin level is associated with coronary heart disease |
topic | Clinical Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564838/ https://www.ncbi.nlm.nih.gov/pubmed/28404934 http://dx.doi.org/10.18632/oncotarget.15707 |
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