Structural homologies between phenformin, lipitor and gleevec aim the same metabolic oncotarget in leukemia and melanoma

Phenformin's recently demonstrated efficacy in melanoma and Gleevec's demonstrated anti-proliferative action in chronic myeloid leukemia may lie within these drugs' significant pharmacokinetics, pharmacodynamics and structural homologies, which are reviewed herein. Gleevec's succ...

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Detalles Bibliográficos
Autores principales: Somlyai, Gábor, Collins, T. Que, Meuillet, Emmanuelle J., Hitendra, Patel, D'Agostino, Dominic P., Boros, László G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564842/
https://www.ncbi.nlm.nih.gov/pubmed/28418852
http://dx.doi.org/10.18632/oncotarget.16238

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