Micrornas in prostate cancer: an overview

Prostate cancer is the second highest cause of cancer mortality after lung tumours. In USA it affects about 2.8 million men and the incidence increases with age in many countries. Therefore, early diagnosis is a very important step for patient clinical evaluation and for a selective and efficient th...

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Autores principales: Vanacore, Daniela, Boccellino, Mariarosaria, Rossetti, Sabrina, Cavaliere, Carla, D'Aniello, Carmine, Di Franco, Rossella, Romano, Francesco Jacopo, Montanari, Micaela, La Mantia, Elvira, Piscitelli, Raffaele, Nocerino, Flavia, Cappuccio, Francesca, Grimaldi, Giovanni, Izzo, Alessandro, Castaldo, Luigi, Pepe, Maria Filomena, Malzone, Maria Gabriella, Iovane, Gelsomina, Ametrano, Gianluca, Stiuso, Paola, Quagliuolo, Lucio, Barberio, Daniela, Perdonà, Sisto, Muto, Paolo, Montella, Maurizio, Maiolino, Piera, Veneziani, Bianca Maria, Botti, Gerardo, Caraglia, Michele, Facchini, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564846/
https://www.ncbi.nlm.nih.gov/pubmed/28445135
http://dx.doi.org/10.18632/oncotarget.16933
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author Vanacore, Daniela
Boccellino, Mariarosaria
Rossetti, Sabrina
Cavaliere, Carla
D'Aniello, Carmine
Di Franco, Rossella
Romano, Francesco Jacopo
Montanari, Micaela
La Mantia, Elvira
Piscitelli, Raffaele
Nocerino, Flavia
Cappuccio, Francesca
Grimaldi, Giovanni
Izzo, Alessandro
Castaldo, Luigi
Pepe, Maria Filomena
Malzone, Maria Gabriella
Iovane, Gelsomina
Ametrano, Gianluca
Stiuso, Paola
Quagliuolo, Lucio
Barberio, Daniela
Perdonà, Sisto
Muto, Paolo
Montella, Maurizio
Maiolino, Piera
Veneziani, Bianca Maria
Botti, Gerardo
Caraglia, Michele
Facchini, Gaetano
author_facet Vanacore, Daniela
Boccellino, Mariarosaria
Rossetti, Sabrina
Cavaliere, Carla
D'Aniello, Carmine
Di Franco, Rossella
Romano, Francesco Jacopo
Montanari, Micaela
La Mantia, Elvira
Piscitelli, Raffaele
Nocerino, Flavia
Cappuccio, Francesca
Grimaldi, Giovanni
Izzo, Alessandro
Castaldo, Luigi
Pepe, Maria Filomena
Malzone, Maria Gabriella
Iovane, Gelsomina
Ametrano, Gianluca
Stiuso, Paola
Quagliuolo, Lucio
Barberio, Daniela
Perdonà, Sisto
Muto, Paolo
Montella, Maurizio
Maiolino, Piera
Veneziani, Bianca Maria
Botti, Gerardo
Caraglia, Michele
Facchini, Gaetano
author_sort Vanacore, Daniela
collection PubMed
description Prostate cancer is the second highest cause of cancer mortality after lung tumours. In USA it affects about 2.8 million men and the incidence increases with age in many countries. Therefore, early diagnosis is a very important step for patient clinical evaluation and for a selective and efficient therapy. The study of miRNAs' functions and molecular mechanisms has brought new knowledge in biological processes of cancer. In prostate cancer there is a deregulation of several miRNAs that may function as tumour suppressors or oncogenes. The aim of this review is to analyze the progress made to our understanding of the role of miRNA dysregulation in prostate cancer tumourigenesis.
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spelling pubmed-55648462017-08-23 Micrornas in prostate cancer: an overview Vanacore, Daniela Boccellino, Mariarosaria Rossetti, Sabrina Cavaliere, Carla D'Aniello, Carmine Di Franco, Rossella Romano, Francesco Jacopo Montanari, Micaela La Mantia, Elvira Piscitelli, Raffaele Nocerino, Flavia Cappuccio, Francesca Grimaldi, Giovanni Izzo, Alessandro Castaldo, Luigi Pepe, Maria Filomena Malzone, Maria Gabriella Iovane, Gelsomina Ametrano, Gianluca Stiuso, Paola Quagliuolo, Lucio Barberio, Daniela Perdonà, Sisto Muto, Paolo Montella, Maurizio Maiolino, Piera Veneziani, Bianca Maria Botti, Gerardo Caraglia, Michele Facchini, Gaetano Oncotarget Review Prostate cancer is the second highest cause of cancer mortality after lung tumours. In USA it affects about 2.8 million men and the incidence increases with age in many countries. Therefore, early diagnosis is a very important step for patient clinical evaluation and for a selective and efficient therapy. The study of miRNAs' functions and molecular mechanisms has brought new knowledge in biological processes of cancer. In prostate cancer there is a deregulation of several miRNAs that may function as tumour suppressors or oncogenes. The aim of this review is to analyze the progress made to our understanding of the role of miRNA dysregulation in prostate cancer tumourigenesis. Impact Journals LLC 2017-04-07 /pmc/articles/PMC5564846/ /pubmed/28445135 http://dx.doi.org/10.18632/oncotarget.16933 Text en Copyright: © 2017 Vanacore et al. http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Review
Vanacore, Daniela
Boccellino, Mariarosaria
Rossetti, Sabrina
Cavaliere, Carla
D'Aniello, Carmine
Di Franco, Rossella
Romano, Francesco Jacopo
Montanari, Micaela
La Mantia, Elvira
Piscitelli, Raffaele
Nocerino, Flavia
Cappuccio, Francesca
Grimaldi, Giovanni
Izzo, Alessandro
Castaldo, Luigi
Pepe, Maria Filomena
Malzone, Maria Gabriella
Iovane, Gelsomina
Ametrano, Gianluca
Stiuso, Paola
Quagliuolo, Lucio
Barberio, Daniela
Perdonà, Sisto
Muto, Paolo
Montella, Maurizio
Maiolino, Piera
Veneziani, Bianca Maria
Botti, Gerardo
Caraglia, Michele
Facchini, Gaetano
Micrornas in prostate cancer: an overview
title Micrornas in prostate cancer: an overview
title_full Micrornas in prostate cancer: an overview
title_fullStr Micrornas in prostate cancer: an overview
title_full_unstemmed Micrornas in prostate cancer: an overview
title_short Micrornas in prostate cancer: an overview
title_sort micrornas in prostate cancer: an overview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564846/
https://www.ncbi.nlm.nih.gov/pubmed/28445135
http://dx.doi.org/10.18632/oncotarget.16933
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