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AB047. Fluid intake-to-bed time, nocturia frequency and the risk of urothelial carcinoma of the bladder: a case-control study

BACKGROUND: To clarify the potential role of fluid intake-to-bed time and nocturia frequency on bladder cancer (BCa) risk in a hospital-based case-control study with Chinese people. METHODS: 407 patients with histologically diagnosed BCa and 400 matched controls were enrolled in this study. Odds rat...

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Autores principales: Cai, Jianfeng, Zhang, Ning, Wang, Shiyu, Yu, Meng, Chen, Shouzhen, Shi, Benkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565545/
http://dx.doi.org/10.21037/tau.2017.s047
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author Cai, Jianfeng
Zhang, Ning
Wang, Shiyu
Yu, Meng
Chen, Shouzhen
Shi, Benkang
author_facet Cai, Jianfeng
Zhang, Ning
Wang, Shiyu
Yu, Meng
Chen, Shouzhen
Shi, Benkang
author_sort Cai, Jianfeng
collection PubMed
description BACKGROUND: To clarify the potential role of fluid intake-to-bed time and nocturia frequency on bladder cancer (BCa) risk in a hospital-based case-control study with Chinese people. METHODS: 407 patients with histologically diagnosed BCa and 400 matched controls were enrolled in this study. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using conditional logistic regression model. RESULTS: The fluid intake-to-bed time was associated with a decreased risk of BCa, with an OR of 0.586 (95% CI: 0.375–0.916, ≤1 h) and 0.257 (95% CI: 0.162–0.407, >1 h). The adjusted ORs of BCa for subjects with more nocturia frequency were 2.268 (95% CI: 1.481–3.474), compared to those with no nocturia. CONCLUSIONS: We suggested strong protective effect of long fluid intake-to-bed time on BCa risk, especially in ones with ≥2 times nocturia frequency. These results provide evidence for identifying high-risk individuals and modifying their behavior and lifestyle.
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spelling pubmed-55655452017-09-01 AB047. Fluid intake-to-bed time, nocturia frequency and the risk of urothelial carcinoma of the bladder: a case-control study Cai, Jianfeng Zhang, Ning Wang, Shiyu Yu, Meng Chen, Shouzhen Shi, Benkang Transl Androl Urol Printed Abstracts BACKGROUND: To clarify the potential role of fluid intake-to-bed time and nocturia frequency on bladder cancer (BCa) risk in a hospital-based case-control study with Chinese people. METHODS: 407 patients with histologically diagnosed BCa and 400 matched controls were enrolled in this study. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using conditional logistic regression model. RESULTS: The fluid intake-to-bed time was associated with a decreased risk of BCa, with an OR of 0.586 (95% CI: 0.375–0.916, ≤1 h) and 0.257 (95% CI: 0.162–0.407, >1 h). The adjusted ORs of BCa for subjects with more nocturia frequency were 2.268 (95% CI: 1.481–3.474), compared to those with no nocturia. CONCLUSIONS: We suggested strong protective effect of long fluid intake-to-bed time on BCa risk, especially in ones with ≥2 times nocturia frequency. These results provide evidence for identifying high-risk individuals and modifying their behavior and lifestyle. AME Publishing Company 2017-08 /pmc/articles/PMC5565545/ http://dx.doi.org/10.21037/tau.2017.s047 Text en 2017 Translational Andrology and Urology. All rights reserved.
spellingShingle Printed Abstracts
Cai, Jianfeng
Zhang, Ning
Wang, Shiyu
Yu, Meng
Chen, Shouzhen
Shi, Benkang
AB047. Fluid intake-to-bed time, nocturia frequency and the risk of urothelial carcinoma of the bladder: a case-control study
title AB047. Fluid intake-to-bed time, nocturia frequency and the risk of urothelial carcinoma of the bladder: a case-control study
title_full AB047. Fluid intake-to-bed time, nocturia frequency and the risk of urothelial carcinoma of the bladder: a case-control study
title_fullStr AB047. Fluid intake-to-bed time, nocturia frequency and the risk of urothelial carcinoma of the bladder: a case-control study
title_full_unstemmed AB047. Fluid intake-to-bed time, nocturia frequency and the risk of urothelial carcinoma of the bladder: a case-control study
title_short AB047. Fluid intake-to-bed time, nocturia frequency and the risk of urothelial carcinoma of the bladder: a case-control study
title_sort ab047. fluid intake-to-bed time, nocturia frequency and the risk of urothelial carcinoma of the bladder: a case-control study
topic Printed Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565545/
http://dx.doi.org/10.21037/tau.2017.s047
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