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AB055. PKCε inhibits isolation and stemness of side population cells via the suppression of ABCB1 transporter and PI3K/Akt, MAPK/ERK signaling in renal cell carcinoma cell line 769P
BACKGROUND: In this study, to identify the function of PKCε in renal cancer stemness of 769P SP cells. METHODS: we reduced the expression of PKCε in 769P cells by using siRNA. Then, the ratios of sorted SP cells were evaluated. Moreover, cancer stem cell (CSC) phenotype of 769P SP cells was assessed...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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AME Publishing Company
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565607/ http://dx.doi.org/10.21037/tau.2017.s055 |