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Up-regulation of Biglycan is Associated with Poor Prognosis and PTEN Deletion in Patients with Prostate Cancer

Biglycan (BGN), a proteoglycan of the extracellular matrix, is included in mRNA signatures for prostate cancer aggressiveness. To understand the impact of BGN on prognosis and its relationship to molecularly defined subsets, we analyzed BGN expression by immunohistochemistry on a tissue microarray c...

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Detalles Bibliográficos
Autores principales:	Jacobsen, Frank, Kraft, Juliane, Schroeder, Cornelia, Hube-Magg, Claudia, Kluth, Martina, Lang, Dagmar S., Simon, Ronald, Sauter, Guido, Izbicki, Jakob R., Clauditz, Till S., Luebke, Andreas M., Hinsch, Andrea, Wilczak, Waldemar, Wittmer, Corinna, Büscheck, Franziska, Höflmayer, Doris, Minner, Sarah, Tsourlakis, Maria Christina, Huland, Hartwig, Graefen, Markus, Budäus, Lars, Thederan, Imke, Salomon, Georg, Schlomm, Thorsten, Melling, Nathaniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2017
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565634/ https://www.ncbi.nlm.nih.gov/pubmed/28830008 http://dx.doi.org/10.1016/j.neo.2017.06.003

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