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NKX2-1 Is Required in the Embryonic Septum for Cholinergic System Development, Learning, and Memory

The transcription factor NKX2-1 is best known for its role in the specification of subsets of cortical, striatal, and pallidal neurons. We demonstrate through genetic fate mapping and intersectional focal septal deletion that NKX2-1 is selectively required in the embryonic septal neuroepithelium for...

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Detalles Bibliográficos
Autores principales: Magno, Lorenza, Barry, Caswell, Schmidt-Hieber, Christoph, Theodotou, Polyvios, Häusser, Michael, Kessaris, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565637/
https://www.ncbi.nlm.nih.gov/pubmed/28813670
http://dx.doi.org/10.1016/j.celrep.2017.07.053