Multipotent Basal Stem Cells, Maintained in Localized Proximal Niches, Support Directed Long-Ranging Epithelial Flows in Human Prostates

Sporadic mitochondrial DNA mutations serve as clonal marks providing access to the identity and lineage potential of stem cells within human tissues. By combining quantitative clonal mapping with 3D reconstruction of adult human prostates, we show that multipotent basal stem cells, confined to discr...

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Detalles Bibliográficos
Autores principales: Moad, Mohammad, Hannezo, Edouard, Buczacki, Simon J., Wilson, Laura, El-Sherif, Amira, Sims, David, Pickard, Robert, Wright, Nicholas A., Williamson, Stuart C., Turnbull, Doug M., Taylor, Robert W., Greaves, Laura, Robson, Craig N., Simons, Benjamin D., Heer, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565638/
https://www.ncbi.nlm.nih.gov/pubmed/28813673
http://dx.doi.org/10.1016/j.celrep.2017.07.061

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