Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter

This data contains information related to the research article entitled “Osteopontin splice variants and polymorphisms in Cancer Progression and Prognosis” [1]. Here, we describe an in silico analysis of transcription factors that could have altered binding to their DNA target sequence as a result o...

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Detalles Bibliográficos
Autores principales: Briones-Orta, Marco Antonio, Avendaño-Vázquez, S. Eréndira, Ivette Aparicio-Bautista, Diana, Coombes, Jason D., Weber, Georg F., Syn, Wing-Kin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Cell biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565761/
https://www.ncbi.nlm.nih.gov/pubmed/28856185
http://dx.doi.org/10.1016/j.dib.2017.07.057
Descripción
Sumario:This data contains information related to the research article entitled “Osteopontin splice variants and polymorphisms in Cancer Progression and Prognosis” [1]. Here, we describe an in silico analysis of transcription factors that could have altered binding to their DNA target sequence as a result of SNPs in the osteopontin gene promoter. We concentrated on SNPs associated with cancer risk and development. The analysis was performed with PROMO v3.0.2 software which incorporates TRANSFACT v6.4 of. We also present a figure depicting the putative transcription factor binding according to genotype.

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