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Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes
With the aim to develop compounds able to target multiple metabolic pathways and, thus, to lower the chances of drug resistance, we investigated the anti-trypanosomal activity and selectivity of a series of symmetric diglycosyl diselenides and disulfides. Of 18 compounds tested the fully acetylated...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565762/ https://www.ncbi.nlm.nih.gov/pubmed/28826037 http://dx.doi.org/10.1016/j.ijpddr.2017.08.001 |