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Direct Monitoring of Protein O-GlcNAcylation by High-Resolution Native Mass Spectrometry
[Image: see text] O-GlcNAcylation is one of the most abundant metazoan nuclear-cytoplasmic post-translational modifications. Proteins modified by O-GlcNAc play key cellular roles in signaling, transcription, metabolism, and cell division. Mechanistic studies on protein O-GlcNAcylation are hampered b...
Autores principales: | Leney, Aneika C., Rafie, Karim, van Aalten, Daan M. F., Heck, Albert J. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565903/ https://www.ncbi.nlm.nih.gov/pubmed/28609614 http://dx.doi.org/10.1021/acschembio.7b00371 |
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