Persistently elevated CKMB and negative troponin T in a patient at ischaemic risk with chest pain

Analytical interference in laboratory assays is not only unpredictable but also an underestimated problem. Not recognising these interferences can lead to misdiagnosis and mismanagement of patients. We present a case of a patient with chest pain and ischaemic risk factors with incongruent biochemica...

Descripción completa

Detalles Bibliográficos
Autores principales: Schulenburg, D, Van Jaarsveld, H, Kuyl, JM, de Lange, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinics Cardive Publishing 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565915/
https://www.ncbi.nlm.nih.gov/pubmed/20224846
Descripción
Sumario:Analytical interference in laboratory assays is not only unpredictable but also an underestimated problem. Not recognising these interferences can lead to misdiagnosis and mismanagement of patients. We present a case of a patient with chest pain and ischaemic risk factors with incongruent biochemical results. These results were discovered to be due to the presence of macro-creatine kinase (macro-CK) in vivo interfering with the CKMB activity assay.

Ejemplares similares