Dynamic relocalization of NHERF1 mediates chemotactic migration of ovarian cancer cells toward lysophosphatidic acid stimulation

NHERF1/EBP50 (Na(+)/H(+) exchanger regulating factor 1; Ezrin-binding phosphoprotein of 50 kDa) organizes stable protein complexes beneath the apical membrane of polar epithelial cells. By contrast, in cancer cells without any fixed polarity, NHERF1 often localizes in the cytoplasm. The regulation o...

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Detalles Bibliográficos
Autores principales: Oh, Yong-Seok, Heo, Kyun, Kim, Eung-Kyun, Jang, Jin-Hyeok, Bae, Sun Sik, Park, Jong Bae, Kim, Yun Hee, Song, Minseok, Kim, Sang Ryong, Ryu, Sung Ho, Kim, In-Hoo, Suh, Pann-Ghill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565956/
https://www.ncbi.nlm.nih.gov/pubmed/28684865
http://dx.doi.org/10.1038/emm.2017.88

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