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Two Distinct Mechanisms Govern RpoS-Mediated Repression of Tick-Phase Genes during Mammalian Host Adaptation by Borrelia burgdorferi, the Lyme Disease Spirochete
The alternative sigma factor RpoS plays a key role modulating gene expression in Borrelia burgdorferi, the Lyme disease spirochete, by transcribing mammalian host-phase genes and repressing σ(70)-dependent genes required within the arthropod vector. To identify cis regulatory elements involved in Rp...
Autores principales: | Grove, Arianna P., Liveris, Dionysios, Iyer, Radha, Petzke, Mary, Rudman, Joseph, Caimano, Melissa J., Radolf, Justin D., Schwartz, Ira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565969/ https://www.ncbi.nlm.nih.gov/pubmed/28830947 http://dx.doi.org/10.1128/mBio.01204-17 |
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