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A new path to platelet production through matrix sensing
Megakaryocytes (MK) in the bone marrow (BM) are immersed in a network of extracellular matrix components that regulates platelet release into the circulation. Combining biological and bioengineering approaches, we found that the activation of transient receptor potential cation channel subfamily V m...
Autores principales: | Abbonante, Vittorio, Di Buduo, Christian Andrea, Gruppi, Cristian, De Maria, Carmelo, Spedden, Elise, De Acutis, Aurora, Staii, Cristian, Raspanti, Mario, Vozzi, Giovanni, Kaplan, David L., Moccia, Francesco, Ravid, Katya, Balduini, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566016/ https://www.ncbi.nlm.nih.gov/pubmed/28411253 http://dx.doi.org/10.3324/haematol.2016.161562 |
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