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A new path to platelet production through matrix sensing

Megakaryocytes (MK) in the bone marrow (BM) are immersed in a network of extracellular matrix components that regulates platelet release into the circulation. Combining biological and bioengineering approaches, we found that the activation of transient receptor potential cation channel subfamily V m...

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Detalles Bibliográficos
Autores principales: Abbonante, Vittorio, Di Buduo, Christian Andrea, Gruppi, Cristian, De Maria, Carmelo, Spedden, Elise, De Acutis, Aurora, Staii, Cristian, Raspanti, Mario, Vozzi, Giovanni, Kaplan, David L., Moccia, Francesco, Ravid, Katya, Balduini, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566016/
https://www.ncbi.nlm.nih.gov/pubmed/28411253
http://dx.doi.org/10.3324/haematol.2016.161562

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