Imatinib and spironolactone suppress hepcidin expression

Disorders of iron metabolism are largely attributed to an excessive or insufficient expression of hepcidin, the master regulator of systemic iron homeostasis. Here, we investigated whether drugs targeting genetic regulators of hepcidin can affect iron homeostasis. We focused our efforts on drugs app...

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Detalles Bibliográficos
Autores principales: Mleczko-Sanecka, Katarzyna, da Silva, Ana Rita, Call, Debora, Neves, Joana, Schmeer, Nikolai, Damm, Georg, Seehofer, Daniel, Muckenthaler, Martina U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566021/
https://www.ncbi.nlm.nih.gov/pubmed/28385785
http://dx.doi.org/10.3324/haematol.2016.162917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566021/
https://www.ncbi.nlm.nih.gov/pubmed/28385785
http://dx.doi.org/10.3324/haematol.2016.162917

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