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Imatinib and spironolactone suppress hepcidin expression
Disorders of iron metabolism are largely attributed to an excessive or insufficient expression of hepcidin, the master regulator of systemic iron homeostasis. Here, we investigated whether drugs targeting genetic regulators of hepcidin can affect iron homeostasis. We focused our efforts on drugs app...
Autores principales: | Mleczko-Sanecka, Katarzyna, da Silva, Ana Rita, Call, Debora, Neves, Joana, Schmeer, Nikolai, Damm, Georg, Seehofer, Daniel, Muckenthaler, Martina U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566021/ https://www.ncbi.nlm.nih.gov/pubmed/28385785 http://dx.doi.org/10.3324/haematol.2016.162917 |
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