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Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis

Immunoglobulin light chain (AL) amyloidosis is a rare plasma cell dyscrasia characterized by the deposition of abnormal amyloid fibrils in multiple organs, thus impairing their function. In the largest cohort studied up to now of 118 CD138-purified plasma cell samples from previously untreated immun...

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Detalles Bibliográficos
Autores principales:	Granzow, Martin, Hegenbart, Ute, Hinderhofer, Katrin, Hose, Dirk, Seckinger, Anja, Bochtler, Tilmann, Hemminki, Kari, Goldschmidt, Hartmut, Schönland, Stefan O., Jauch, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566044/ https://www.ncbi.nlm.nih.gov/pubmed/28341732 http://dx.doi.org/10.3324/haematol.2016.160721

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