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RBFOX3 Promotes Tumor Growth and Progression via hTERT Signaling and Predicts a Poor Prognosis in Hepatocellular Carcinoma

Activation of the telomere maintenance mechanism is a key hallmark of cancer. Human telomerase reverse transcriptase (hTERT) is the catalytic subunit of telomerase, which is highly expressed in more than 80% of tumors, including hepatocellular carcinoma (HCC). However, the exact mechanisms by which...

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Detalles Bibliográficos
Autores principales: Liu, Tianze, Li, Wenbin, Lu, Wenjing, Chen, Miao, Luo, Meihua, Zhang, Changlin, Li, Yixin, Qin, Ge, Shi, Dingbo, Xiao, Binyi, Qiu, Huijuan, Yu, Wendan, Kang, Lan, Kang, Tiebang, Huang, Wenlin, Yu, Xinfa, Wu, Xiaojun, Deng, Wuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566111/
https://www.ncbi.nlm.nih.gov/pubmed/28839469
http://dx.doi.org/10.7150/thno.19506