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APMAP interacts with lysyl oxidase–like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion

Adipocyte plasma membrane–associated protein (APMAP) has been described as an adipogenic factor in 3T3-L1 cells with unknown biochemical function; we therefore aimed to investigate the physiologic function of APMAP in vivo. We generated Apmap-knockout mice and challenged them with an obesogenic diet...

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Detalles Bibliográficos
Autores principales: Pessentheiner, Ariane R., Huber, Katharina, Pelzmann, Helmut J., Prokesch, Andreas, Radner, Franz P. W., Wolinski, Heimo, Lindroos-Christensen, Josefine, Hoefler, Gerald, Rülicke, Thomas, Birner-Gruenberger, Ruth, Bilban, Martin, Bogner-Strauss, Juliane G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566180/
https://www.ncbi.nlm.nih.gov/pubmed/28559441
http://dx.doi.org/10.1096/fj.201601337R