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The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties

IL-17A and IL-17F are prominent members of the IL-17 family of cytokines that regulates both innate and adaptive immunity. IL-17A has been implicated in chronic inflammatory and autoimmune diseases, and anti-IL-17A antibodies have shown remarkable clinical efficacy in psoriasis and psoriatic arthrit...

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Detalles Bibliográficos
Autores principales: Goepfert, Arnaud, Lehmann, Sylvie, Wirth, Emmanuelle, Rondeau, Jean-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566378/
https://www.ncbi.nlm.nih.gov/pubmed/28827714
http://dx.doi.org/10.1038/s41598-017-08360-9

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