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A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate

Monoterpene indole alkaloids comprise a diverse family of over 2000 plant-produced natural products. This pathway provides an outstanding example of how nature creates chemical diversity from a single precursor, in this case from the intermediate strictosidine. The enzymes that elicit these seemingl...

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Detalles Bibliográficos
Autores principales: Tatsis, Evangelos C., Carqueijeiro, Inês, Dugé de Bernonville, Thomas, Franke, Jakob, Dang, Thu-Thuy T., Oudin, Audrey, Lanoue, Arnaud, Lafontaine, Florent, Stavrinides, Anna K., Clastre, Marc, Courdavault, Vincent, O’Connor, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566405/
https://www.ncbi.nlm.nih.gov/pubmed/28827772
http://dx.doi.org/10.1038/s41467-017-00154-x