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Baicalein prevents 6-OHDA/ascorbic acid-induced calcium-dependent dopaminergic neuronal cell death

6-OHDA plus ascorbic acid (AA) has long been used to induce Parkinson’s disease in rodents, while only 6-OHDA is commonly used to induce cell damage in cellular PD models. AA was believed to act as an anti-oxidant to prevent the degradation of 6-OHDA; however, some studies suggested that AA dramatic...

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Detalles Bibliográficos
Autores principales: Wang, Sheng-Fang, Liu, Liang-Feng, Wu, Ming-Yue, Cai, Cui-Zan, Su, Huanxing, Tan, Jieqiong, Lu, Jia-Hong, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566482/
https://www.ncbi.nlm.nih.gov/pubmed/28827552
http://dx.doi.org/10.1038/s41598-017-07142-7

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