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Pharmacokinetic and Pharmacodynamic Evaluation of Marbofloxacin and PK/PD Modeling against Escherichia coli in Pigs

The aim of this study was to evaluate the activity of marbofloxacin and establish the optimal dose regimens for decreasing the development of fluoroquinolone resistance in pigs against Escherichia coli with ex vivo pharmacokinetic/pharmacodynamic (PK/PD) modeling. The recommended dose (2 mg/kg body...

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Detalles Bibliográficos
Autores principales:	Lei, Zhixin, Liu, Qianying, Xiong, Jincheng, Yang, Bing, Yang, Shuaike, Zhu, Qianqian, Li, Kun, Zhang, Shishuo, Cao, Jiyue, He, Qigai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566571/ https://www.ncbi.nlm.nih.gov/pubmed/28871226 http://dx.doi.org/10.3389/fphar.2017.00542

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