P2X7 Receptor Activation Modulates Autophagy in SOD1-G93A Mouse Microglia

Autophagy and inflammation play determinant roles in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS), an adult-onset neurodegenerative disease characterized by deterioration and final loss of upper and lower motor neurons (MN) priming microglia to sustain neuroinflammation and a vicious cycl...

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Detalles Bibliográficos
Autores principales: Fabbrizio, Paola, Amadio, Susanna, Apolloni, Savina, Volonté, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566572/
https://www.ncbi.nlm.nih.gov/pubmed/28871219
http://dx.doi.org/10.3389/fncel.2017.00249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566572/
https://www.ncbi.nlm.nih.gov/pubmed/28871219
http://dx.doi.org/10.3389/fncel.2017.00249

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