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Integration of Metabolomics and Transcriptomics Reveals a Complex Diet of Mycobacterium tuberculosis during Early Macrophage Infection

Nutrient acquisition from the host environment is crucial for the survival of intracellular pathogens, but conceptual and technical challenges limit our knowledge of pathogen diets. To overcome some of these technical roadblocks, we exploited an experimentally accessible model for early infection of...

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Detalles Bibliográficos
Autores principales: Zimmermann, Michael, Kogadeeva, Maria, Gengenbacher, Martin, McEwen, Gayle, Mollenkopf, Hans-Joachim, Zamboni, Nicola, Kaufmann, Stefan Hugo Ernst, Sauer, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566787/
https://www.ncbi.nlm.nih.gov/pubmed/28845460
http://dx.doi.org/10.1128/mSystems.00057-17