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Low TIM3 expression indicates poor prognosis of metastatic prostate cancer and acts as an independent predictor of castration resistant status
T cell immunoglobulin 3 (TIM3) is a cell surface star molecule expressed on T cells, and also marks dysfunctional CD8(+) T cells in various kinds of cancers. However, there are few studies focusing on the expression of TIM3 in tumor cells. In our study, we recruited 139 patients with metastatic pros...
Autores principales: | Wu, Junlong, Lin, Guowen, Zhu, Yao, Zhang, Hailiang, Shi, Guohai, Shen, Yijun, Zhu, Yiping, Dai, Bo, Ye, Dingwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567055/ https://www.ncbi.nlm.nih.gov/pubmed/28827755 http://dx.doi.org/10.1038/s41598-017-09484-8 |
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