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Degradation of cofilin is regulated by Cbl, AIP4 and Syk resulting in increased migration of LMP2A positive nasopharyngeal carcinoma cells

Expression of cofilin is directly associated with metastatic activity in many tumors. Here, we studied the role of Latent Membrane Protein 2 A (LMP2A) of Epstein-Barr Virus (EBV) in the accumulation of cofilin observed in nasopharyngeal cancer (NPC) tumor cells. We used LMP2A transformed NPC cell li...

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Detalles Bibliográficos
Autores principales: Gainullin, Murat R., Zhukov, Ilya Yu, Zhou, Xiaoying, Mo, Yingxi, Astakhova, Lidiia, Ernberg, Ingemar, Matskova, Liudmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567079/
https://www.ncbi.nlm.nih.gov/pubmed/28827787
http://dx.doi.org/10.1038/s41598-017-09540-3

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