Cargando…

Ceramide phosphoethanolamine synthase SMSr is a target of caspase-6 during apoptotic cell death

Ceramides are essential precursors of sphingolipids with a dual role as mediators of apoptotic cell death. Previous work revealed that the ER-resident ceramide phosphoethanolamine (CPE) synthase SMSr/SAMD8 is a suppressor of ceramide-mediated apoptosis in cultured cells. Anti-apoptotic activity of S...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cabukusta, Birol, Nettebrock, Niclas T., Kol, Matthijs, Hilderink, Angelika, Tafesse, Fikadu G., Holthuis, Joost C.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567093/ https://www.ncbi.nlm.nih.gov/pubmed/28659495 http://dx.doi.org/10.1042/BSR20170867

Ejemplares similares

ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain
por: Cabukusta, Birol, et al.
Publicado: (2017)

Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER
por: Vacaru, Ana M., et al.
Publicado: (2009)

Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides
por: Kol, Matthijs, et al.
Publicado: (2019)

Ceramide Phosphoethanolamine as a Possible Marker of Periodontal Disease
por: Grundner, Maja, et al.
Publicado: (2022)

Formation of tubules and helical ribbons by ceramide phosphoethanolamine-containing membranes
por: Inaba, Takehiko, et al.
Publicado: (2019)

Unraveling the molecular principles by which ceramides commit cells to death
por: Dadsena, Shashank, et al.
Publicado: (2019)

Sphingomyelin synthase–related protein SMSr is a phosphatidylethanolamine phospholipase C that promotes nonalcoholic fatty liver disease
por: Chiang, Yeun-po, et al.
Publicado: (2023)

Ceramides bind VDAC2 to trigger mitochondrial apoptosis
por: Dadsena, Shashank, et al.
Publicado: (2019)

Ceramide synthase 2 deletion decreases the infectivity of HIV-1
por: Barklis, Eric, et al.
Publicado: (2021)

Endogenous ceramide phosphoethanolamine modulates circadian rhythm via neural–glial coupling in Drosophila
por: Chen, Xiupeng, et al.
Publicado: (2022)

Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis
por: Kunduri, Govind, et al.
Publicado: (2022)

A Global In Vivo Drosophila RNAi Screen Identifies a Key Role of Ceramide Phosphoethanolamine for Glial Ensheathment of Axons
por: Ghosh, Aniket, et al.
Publicado: (2013)

Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway
por: Sokoya, Tolulope, et al.
Publicado: (2022)

Phosphoethanolamine and the danger of unproven drugs
por: Pondé, Noam, et al.
Publicado: (2016)

Apoptotic Sphingolipid Ceramide in Cancer Therapy
por: Huang, Wei-Ching, et al.
Publicado: (2011)

Mechanisms of lysosomal positioning and movement
por: Cabukusta, Birol, et al.
Publicado: (2018)

What the VAP: The Expanded VAP Family of Proteins Interacting With FFAT and FFAT-Related Motifs for Interorganellar Contact
por: Neefjes, Jacques, et al.
Publicado: (2021)

Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase 3 in colon cancer cells
por: White-Gilbertson, S., et al.
Publicado: (2009)

Horse-Derived Ceramide Accentuates Glucosylceramide Synthase and Ceramide Synthase 3 by Activating PPARβ/δ and/or PPARγ to Stimulate Ceramide Synthesis
por: Igarashi, Tami, et al.
Publicado: (2023)

Ceramide Synthases Expression and Role of Ceramide Synthase-2 in the Lung: Insight from Human Lung Cells and Mouse Models
por: Petrache, Irina, et al.
Publicado: (2013)

Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell Entry
por: Niekamp, Patrick, et al.
Publicado: (2021)

Pore-forming protein complexes from Pleurotus mushrooms kill western corn rootworm and Colorado potato beetle through targeting membrane ceramide phosphoethanolamine
por: Panevska, Anastasija, et al.
Publicado: (2019)

Glycogen Synthase Kinase-3β and Caspase-2 Mediate Ceramide- and Etoposide-Induced Apoptosis by Regulating the Lysosomal-Mitochondrial Axis
por: Lin, Chiou-Feng, et al.
Publicado: (2016)

Are membranes non-apoptotic compartments for apoptotic caspases?
por: Bergmann, Andreas
Publicado: (2018)

The Role of Ceramide Synthases in the Pathogenicity of Cryptococcus neoformans
por: Munshi, Mansa A., et al.
Publicado: (2018)

Accumulation of Phosphoethanolamine in the Livers of Rats Injected with Hepatocarcinogens
por: Neish, W. J. P., et al.
Publicado: (1960)

Bioinspired Nanoemulsions Stabilized by Phosphoethanolamine and Phosphoglycerol Lipids
por: Caianiello, Carlo, et al.
Publicado: (2020)

A tissue‐specific screen of ceramide expression in aged mice identifies ceramide synthase‐1 and ceramide synthase‐5 as potential regulators of fiber size and strength in skeletal muscle
por: Tosetti, Bettina, et al.
Publicado: (2019)

The Swiss Multiple Sclerosis Registry (SMSR): study protocol of a participatory, nationwide registry to promote epidemiological and patient-centered MS research
por: Steinemann, Nina, et al.
Publicado: (2018)

Oxidized Phospholipids Induce Ceramide Accumulation in RAW 264.7 Macrophages: Role of Ceramide Synthases
por: Halasiddappa, Lingaraju M., et al.
Publicado: (2013)

Silencing of ceramide synthase 2 in hepatocytes modulates plasma ceramide biomarkers predictive of cardiovascular death
por: Schmidt, Steffen, et al.
Publicado: (2022)

Fatty acid transport protein 2 interacts with ceramide synthase 2 to promote ceramide synthesis
por: Kim, Jiyoon L., et al.
Publicado: (2022)

Ceramide Synthase 6: Comparative Analysis, Phylogeny and Evolution
por: Holmes, Roger S., et al.
Publicado: (2018)

Anti-Angiogenic and Anti-Metastatic Activity of Synthetic Phosphoethanolamine
por: Ferreira, Adilson Kleber, et al.
Publicado: (2013)

Overexpression of ceramide synthase 1 increases C18-ceramide and leads to lethal autophagy in human glioma
por: Wang, Zheng, et al.
Publicado: (2017)

Ceramide compensation by ceramide synthases preserves retinal function and structure in a retinal dystrophy mouse model
por: Qian, Xinye, et al.
Publicado: (2023)

Non-Apoptotic Role of Apoptotic Caspases in the Drosophila Nervous System
por: Colon-Plaza, Sarah, et al.
Publicado: (2022)

An overview of caspase: Apoptotic protein for silicosis
por: Tumane, Rajani G., et al.
Publicado: (2010)

Lipidomics Suggests a New Role for Ceramide Synthase in Phagocytosis
por: Pathak, Divya, et al.
Publicado: (2018)

Ceramide Synthases Are Attractive Drug Targets for Treating Metabolic Diseases
por: Raichur, Suryaprakash
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oa6a8vj53fp702vln0vjh927f2