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Analysis of mononucleotides by tandem mass spectrometry: investigation of fragmentation pathways for phosphate- and ribose-modified nucleotide analogues

Synthetic nucleotide and nucleic acid analogues are useful research tools and modern therapeutics. Hence, methods for the rapid and unambiguous identification of mononucleotides derived from organic syntheses or biological materials are of broad interest. Here, we analysed over 150 mononucleotides (...

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Detalles Bibliográficos
Autores principales: Strzelecka, Dominika, Chmielinski, Sebastian, Bednarek, Sylwia, Jemielity, Jacek, Kowalska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567097/
https://www.ncbi.nlm.nih.gov/pubmed/28827558
http://dx.doi.org/10.1038/s41598-017-09416-6