Diethylstilbestrol administration inhibits theca cell androgen and granulosa cell estrogen production in immature rat ovary

Diethylstilbestrol (DES), a strong estrogenic compound, is well-known to affect the reproductive system. In this study, we investigated the effects of DES administration on gonadotropin levels and ovarian steroidogenesis in prepubertal rats. DES treatment acutely reduced serum LH levels, followed by...

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Detalles Bibliográficos
Autores principales: Imamichi, Yoshitaka, Sekiguchi, Toshio, Kitano, Takeshi, Kajitani, Takashi, Okada, Reiko, Inaoka, Yoshihiko, Miyamoto, Kaoru, Uwada, Junsuke, Takahashi, Satoru, Nemoto, Takahiro, Mano, Asuka, Khan, Md Rafiqul Islam, Islam, Md Tariqul, Yuhki, Koh-ichi, Kashiwagi, Hitoshi, Ushikubi, Fumitaka, Suzuki, Nobuo, Taniguchi, Takanobu, Yazawa, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567288/
https://www.ncbi.nlm.nih.gov/pubmed/28827713
http://dx.doi.org/10.1038/s41598-017-08780-7

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