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GLP-1/Exendin-4 induces β-cell proliferation via the epidermal growth factor receptor
Exendin-4 is a long acting glucagon-like peptide 1 (GLP-1) analogue that is an agonist for the GLP-1 receptor, a G-protein coupled receptor (GPCR). Exendin-4 is used to clinically improve glucose tolerance in diabetic patients due to its ability to enhance insulin secretion. In rodents, and possibly...
Autores principales: | Fusco, Joseph, Xiao, Xiangwei, Prasadan, Krishna, Sheng, Qingfeng, Chen, Congde, Ming, Yung-Ching, Gittes, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567347/ https://www.ncbi.nlm.nih.gov/pubmed/28831150 http://dx.doi.org/10.1038/s41598-017-09898-4 |
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