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CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects
OBJECTIVE—: Lp(a) [lipoprotein (a)] is composed of apoB (apolipoprotein B) and apo(a) [apolipoprotein (a)] and is an independent risk factor for cardiovascular disease and aortic stenosis. In clinical trials, anacetrapib, a CETP (cholesteryl ester transfer protein) inhibitor, causes significant redu...
Autores principales: | Thomas, Tiffany, Zhou, Haihong, Karmally, Wahida, Ramakrishnan, Rajasekhar, Holleran, Stephen, Liu, Yang, Jumes, Patricia, Wagner, John A., Hubbard, Brian, Previs, Stephen F., Roddy, Thomas, Johnson-Levonas, Amy O., Gutstein, David E., Marcovina, Santica M., Rader, Daniel J., Ginsberg, Henry N., Millar, John S., Reyes-Soffer, Gissette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567403/ https://www.ncbi.nlm.nih.gov/pubmed/28729361 http://dx.doi.org/10.1161/ATVBAHA.117.309549 |
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