Motor impairment and compensation in a hemiparkinsonian rat model: correlation between dopamine depletion severity, cerebral metabolism and gait patterns

BACKGROUND: In Parkinson’s disease (PD), cerebral dopamine depletion is associated with PD subtype-specific metabolic patterns of hypo- and hypermetabolism. It has been hypothesised that hypometabolism reflects impairment, while hypermetabolism may indicate compensatory activity. In order to associa...

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Detalles Bibliográficos
Autores principales: Kordys, Elena, Apetz, Nadine, Schneider, Katharina, Duncan, Eilidh, Büschbell, Beatriz, Rohleder, Cathrin, Sué, Michael, Drzezga, Alexander, Neumaier, Bernd, Timmermann, Lars, Endepols, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567589/
https://www.ncbi.nlm.nih.gov/pubmed/28831764
http://dx.doi.org/10.1186/s13550-017-0317-9

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