Dendrimer-doxorubicin conjugates exhibit improved anticancer activity and reduce doxorubicin-induced cardiotoxicity in a murine hepatocellular carcinoma model

Hepatocellular carcinoma (HCC) is the 2(nd) leading cause of cancer-related deaths every year globally. The most common form of treatment, hepatic arterial infusion (HAI), involves the direct injection of doxorubicin (DOX) into the hepatic artery. It is plagued with limited therapeutic efficacy and...

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Detalles Bibliográficos
Autores principales: Kuruvilla, Sibu P., Tiruchinapally, Gopinath, Crouch, A. Colleen, ElSayed, Mohamed E. H., Greve, Joan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567696/
https://www.ncbi.nlm.nih.gov/pubmed/28829785
http://dx.doi.org/10.1371/journal.pone.0181944

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