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A coiled conformation of amyloid-β recognized by antibody C706

BACKGROUND: β-Amyloid (Aβ) peptide is believed to play a pivotal role in the development of Alzheimer’s disease. Passive immunization with anti-Aβ monoclonal antibodies may facilitate the clearance of Aβ in the brain and may thus prevent the downstream pathology. Antibodies targeting the immunodomin...

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Detalles Bibliográficos
Autores principales: Teplyakov, Alexey, Obmolova, Galina, Gilliland, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568176/
https://www.ncbi.nlm.nih.gov/pubmed/28830506
http://dx.doi.org/10.1186/s13195-017-0296-0