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A coiled conformation of amyloid-β recognized by antibody C706
BACKGROUND: β-Amyloid (Aβ) peptide is believed to play a pivotal role in the development of Alzheimer’s disease. Passive immunization with anti-Aβ monoclonal antibodies may facilitate the clearance of Aβ in the brain and may thus prevent the downstream pathology. Antibodies targeting the immunodomin...
Autores principales: | Teplyakov, Alexey, Obmolova, Galina, Gilliland, Gary L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568176/ https://www.ncbi.nlm.nih.gov/pubmed/28830506 http://dx.doi.org/10.1186/s13195-017-0296-0 |
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