Fructose diet alleviates acetaminophen-induced hepatotoxicity in mice

Acetaminophen (APAP) is a commonly used analgesic and antipyretic that can cause hepatotoxicity due to production of toxic metabolites via cytochrome P450 (Cyp) 1a2 and Cyp2e1. Previous studies have shown conflicting effects of fructose (the major component in Western diet) on the susceptibility to...

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Detalles Bibliográficos
Autores principales: Cho, Sungjoon, Tripathi, Ashutosh, Chlipala, George, Green, Stefan, Lee, Hyunwoo, Chang, Eugene B., Jeong, Hyunyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568217/
https://www.ncbi.nlm.nih.gov/pubmed/28832650
http://dx.doi.org/10.1371/journal.pone.0182977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568217/
https://www.ncbi.nlm.nih.gov/pubmed/28832650
http://dx.doi.org/10.1371/journal.pone.0182977

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