High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture

BACKGROUND: Alzheimer’s Disease (AD), characterized by accumulation of beta-amyloid (Aβ) plaques in the brain, can be caused by age-related failures to clear Aβ from the brain through pathways that involve the cerebrovasculature. Vascular risk factors are known to increase AD risk, but less is known...

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Detalles Bibliográficos
Autores principales: Robert, Jérôme, Button, Emily B., Stukas, Sophie, Boyce, Guilaine K., Gibbs, Ebrima, Cowan, Catherine M., Gilmour, Megan, Cheng, Wai Hang, Soo, Sonja K., Yuen, Brian, Bahrabadi, Arvin, Kang, Kevin, Kulic, Iva, Francis, Gordon, Cashman, Neil, Wellington, Cheryl L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568306/
https://www.ncbi.nlm.nih.gov/pubmed/28830501
http://dx.doi.org/10.1186/s13024-017-0201-0

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