Assessment of the prognostic role of a 94-single nucleotide polymorphisms risk score in early breast cancer in the SIGNAL/PHARE prospective cohort: no correlation with clinico-pathological characteristics and outcomes

BACKGROUND: Genome-wide association studies (GWAS) have to date identified 94 genetic variants (single nucleotide polymorphisms (SNPs)) associated with risk of developing breast cancer. A score based on the combined effect of the 94 risk alleles can be calculated to measure the global risk of breast...

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Detalles Bibliográficos
Autores principales: Curtit, Elsa, Pivot, Xavier, Henriques, Julie, Paget-Bailly, Sophie, Fumoleau, Pierre, Rios, Maria, Bonnefoi, Hervé, Bachelot, Thomas, Soulié, Patrick, Jouannaud, Christelle, Bourgeois, Hugues, Petit, Thierry, Tennevet, Isabelle, Assouline, David, Mathieu, Marie-Christine, Jacquin, Jean-Philippe, Lavau-Denes, Sandrine, Darut-Jouve, Ariane, Ferrero, Jean-Marc, Tarpin, Carole, Lévy, Christelle, Delecroix, Valérie, Trillet-Lenoir, Véronique, Cojocarasu, Oana, Meunier, Jérôme, Pierga, Jean-Yves, Kerbrat, Pierre, Faure-Mercier, Céline, Blanché, Hélène, Sahbatou, Mourad, Boland, Anne, Bacq, Delphine, Besse, Céline, Thomas, Gilles, Deleuze, Jean-François, Pauporté, Iris, Romieu, Gilles, Cox, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568360/
https://www.ncbi.nlm.nih.gov/pubmed/28830573
http://dx.doi.org/10.1186/s13058-017-0888-4

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