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Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APP(NL-F) mouse model of Alzheimer disease

Alzheimer disease (AD) stands out amongst highly prevalent diseases because there is no effective treatment nor can the disease be reliably diagnosed at an early stage. A hallmark of AD is the accumulation of aggregation-prone amyloid β peptides (Aβ), the main constituent of amyloid plaques. To iden...

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Detalles Bibliográficos
Autores principales:	Wang, Hansen, Williams, Declan, Griffin, Jennifer, Saito, Takashi, Saido, Takaomi C., Fraser, Paul E., Rogaeva, Ekaterina, Schmitt-Ulms, Gerold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568403/ https://www.ncbi.nlm.nih.gov/pubmed/28832675 http://dx.doi.org/10.1371/journal.pone.0182844

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