Metabolic control of the scaffold protein TKS5 in tissue-invasive, pro-inflammatory T cells

Pathogenic T cells in rheumatoid arthritis (RA) infiltrate non-lymphoid tissue sites, maneuver through extra-cellular matrix and form lasting inflammatory microstructures. Here, we found that RA T cells abundantly express the podosome scaffolding protein TKS5, enabling them to form tissue-invasive m...

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Detalles Bibliográficos
Autores principales: Shen, Yi, Wen, Zhenke, Li, Yinyin, Matteson, Eric L., Hong, Jison, Goronzy, Jörg J., Weyand, Cornelia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568495/
https://www.ncbi.nlm.nih.gov/pubmed/28737753
http://dx.doi.org/10.1038/ni.3808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568495/
https://www.ncbi.nlm.nih.gov/pubmed/28737753
http://dx.doi.org/10.1038/ni.3808

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