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Influence of parameter perturbations on the reachability of therapeutic target in systems with switchings
BACKGROUND: Examination of physiological processes and the influences of the drugs on them can be efficiently supported by mathematical modeling. One of the biggest problems is related to the exact fitting of the parameters of a model. Conditions inside the organism change dynamically, so the rates...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568638/ https://www.ncbi.nlm.nih.gov/pubmed/28830427 http://dx.doi.org/10.1186/s12938-017-0360-9 |