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Preclinical and Clinical Data for Factor Xa and “Universal” Reversal Agents

Oral Factor Xa (FXa) inhibitors, a growing class of direct-acting anticoagulants, are frequently used to prevent stroke and systemic embolism in patients with atrial fibrillation and to prevent and treat venous thromboembolism. These drugs reduce the risk of clotting at the expense of increasing the...

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Detalles Bibliográficos
Autores principales: Milling, Truman J., Kaatz, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568764/
https://www.ncbi.nlm.nih.gov/pubmed/27575436
http://dx.doi.org/10.1016/j.amjmed.2016.06.009