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Establishment and genomic characterization of the new chordoma cell line Chor-IN-1
Chordomas are rare, slowly growing tumors with high medical need, arising in the axial skeleton from notochord remnants. The transcription factor “brachyury” represents a distinctive molecular marker and a key oncogenic driver of chordomas. Tyrosine kinase receptors are also expressed, but so far ki...
Autores principales: | Bosotti, Roberta, Magnaghi, Paola, Di Bella, Sebastiano, Cozzi, Liviana, Cusi, Carlo, Bozzi, Fabio, Beltrami, Nicola, Carapezza, Giovanni, Ballinari, Dario, Amboldi, Nadia, Lupi, Rosita, Somaschini, Alessio, Raddrizzani, Laura, Salom, Barbara, Galvani, Arturo, Stacchiotti, Silvia, Tamborini, Elena, Isacchi, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569021/ https://www.ncbi.nlm.nih.gov/pubmed/28835717 http://dx.doi.org/10.1038/s41598-017-10044-3 |
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