The small GTPase, nucleolar GTP-binding protein 1 (NOG1), has a novel role in plant innate immunity

Plant defense responses at stomata and apoplast are the most important early events during plant-bacteria interactions. The key components for the signaling of stomatal defense and nonhost resistance have not been fully characterized. Here we report the newly identified small GTPase, Nucleolar GTP-b...

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Autores principales: Lee, Seonghee, Senthil-Kumar, Muthappa, Kang, Miyoung, Rojas, Clemencia M., Tang, Yuhong, Oh, Sunhee, Choudhury, Swarup Roy, Lee, Hee-Kyung, Ishiga, Yasuhiro, Allen, Randy D., Pandey, Sona, Mysore, Kirankumar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569028/
https://www.ncbi.nlm.nih.gov/pubmed/28835689
http://dx.doi.org/10.1038/s41598-017-08932-9
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author Lee, Seonghee
Senthil-Kumar, Muthappa
Kang, Miyoung
Rojas, Clemencia M.
Tang, Yuhong
Oh, Sunhee
Choudhury, Swarup Roy
Lee, Hee-Kyung
Ishiga, Yasuhiro
Allen, Randy D.
Pandey, Sona
Mysore, Kirankumar S.
author_facet Lee, Seonghee
Senthil-Kumar, Muthappa
Kang, Miyoung
Rojas, Clemencia M.
Tang, Yuhong
Oh, Sunhee
Choudhury, Swarup Roy
Lee, Hee-Kyung
Ishiga, Yasuhiro
Allen, Randy D.
Pandey, Sona
Mysore, Kirankumar S.
author_sort Lee, Seonghee
collection PubMed
description Plant defense responses at stomata and apoplast are the most important early events during plant-bacteria interactions. The key components for the signaling of stomatal defense and nonhost resistance have not been fully characterized. Here we report the newly identified small GTPase, Nucleolar GTP-binding protein 1 (NOG1), functions for plant immunity against bacterial pathogens. Virus-induced gene silencing of NOG1 compromised nonhost resistance in N. benthamiana and tomato. Comparative genomic analysis showed that two NOG1 copies are present in all known plant species: NOG1-1 and NOG1-2. Gene downregulation and overexpression studies of NOG1-1 and NOG1-2 in Arabidopsis revealed the novel function of these genes in nonhost resistance and stomatal defense against bacterial pathogens, respectively. Specially, NOG1-2 regulates guard cell signaling in response to biotic and abiotic stimuli through jasmonic acid (JA)- and abscisic acid (ABA)-mediated pathways. The results here provide valuable information on the new functional role of small GTPase, NOG1, in guard cell signaling and early plant defense in response to bacterial pathogens.
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spelling pubmed-55690282017-09-01 The small GTPase, nucleolar GTP-binding protein 1 (NOG1), has a novel role in plant innate immunity Lee, Seonghee Senthil-Kumar, Muthappa Kang, Miyoung Rojas, Clemencia M. Tang, Yuhong Oh, Sunhee Choudhury, Swarup Roy Lee, Hee-Kyung Ishiga, Yasuhiro Allen, Randy D. Pandey, Sona Mysore, Kirankumar S. Sci Rep Article Plant defense responses at stomata and apoplast are the most important early events during plant-bacteria interactions. The key components for the signaling of stomatal defense and nonhost resistance have not been fully characterized. Here we report the newly identified small GTPase, Nucleolar GTP-binding protein 1 (NOG1), functions for plant immunity against bacterial pathogens. Virus-induced gene silencing of NOG1 compromised nonhost resistance in N. benthamiana and tomato. Comparative genomic analysis showed that two NOG1 copies are present in all known plant species: NOG1-1 and NOG1-2. Gene downregulation and overexpression studies of NOG1-1 and NOG1-2 in Arabidopsis revealed the novel function of these genes in nonhost resistance and stomatal defense against bacterial pathogens, respectively. Specially, NOG1-2 regulates guard cell signaling in response to biotic and abiotic stimuli through jasmonic acid (JA)- and abscisic acid (ABA)-mediated pathways. The results here provide valuable information on the new functional role of small GTPase, NOG1, in guard cell signaling and early plant defense in response to bacterial pathogens. Nature Publishing Group UK 2017-08-23 /pmc/articles/PMC5569028/ /pubmed/28835689 http://dx.doi.org/10.1038/s41598-017-08932-9 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Lee, Seonghee
Senthil-Kumar, Muthappa
Kang, Miyoung
Rojas, Clemencia M.
Tang, Yuhong
Oh, Sunhee
Choudhury, Swarup Roy
Lee, Hee-Kyung
Ishiga, Yasuhiro
Allen, Randy D.
Pandey, Sona
Mysore, Kirankumar S.
The small GTPase, nucleolar GTP-binding protein 1 (NOG1), has a novel role in plant innate immunity
title The small GTPase, nucleolar GTP-binding protein 1 (NOG1), has a novel role in plant innate immunity
title_full The small GTPase, nucleolar GTP-binding protein 1 (NOG1), has a novel role in plant innate immunity
title_fullStr The small GTPase, nucleolar GTP-binding protein 1 (NOG1), has a novel role in plant innate immunity
title_full_unstemmed The small GTPase, nucleolar GTP-binding protein 1 (NOG1), has a novel role in plant innate immunity
title_short The small GTPase, nucleolar GTP-binding protein 1 (NOG1), has a novel role in plant innate immunity
title_sort small gtpase, nucleolar gtp-binding protein 1 (nog1), has a novel role in plant innate immunity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569028/
https://www.ncbi.nlm.nih.gov/pubmed/28835689
http://dx.doi.org/10.1038/s41598-017-08932-9
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