Leukocytic Toll-Like Receptor 2 Deficiency Preserves Cardiac Function And Reduces Fibrosis In Sustained Pressure Overload

An involement of Toll-like receptor 2 (TLR2) has been established in cardiac dysfunction after acute myocardial infarction; however, its role in chronic pressure overload is unclear. We sought to evaluate the role of TLR2 in cardiac hypertrophy, fibrosis and dysfunction in sustained pressure overloa...

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Detalles Bibliográficos
Autores principales: Wang, Jiong-Wei, Fontes, Magda S. C., Wang, Xiaoyuan, Chong, Suet Yen, Kessler, Elise L., Zhang, Ya-Nan, de Haan, Judith J., Arslan, Fatih, de Jager, Saskia C. A., Timmers, Leo, van Veen, Toon A. B., Lam, Carolyn S. P., Kleijn, Dominique P. V. de
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569043/
https://www.ncbi.nlm.nih.gov/pubmed/28835616
http://dx.doi.org/10.1038/s41598-017-09451-3

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