Development of a versatile and conventional technique for gene disruption in filamentous fungi based on CRISPR-Cas9 technology

Filamentous fungi represent an invaluable source of pharmaceutically active compounds. The development of versatile methods to genetically manipulate filamentous fungi is of great value for improving the low yields of bioactive metabolites and expanding chemical diversity. The CRISPR-Cas9-based syst...

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Detalles Bibliográficos
Autores principales: Zheng, Yan-Mei, Lin, Fu-Long, Gao, Hao, Zou, Gen, Zhang, Jiang-Wei, Wang, Gao-Qian, Chen, Guo-Dong, Zhou, Zhi-Hua, Yao, Xin-Sheng, Hu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569088/
https://www.ncbi.nlm.nih.gov/pubmed/28835711
http://dx.doi.org/10.1038/s41598-017-10052-3

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